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One-step PCR: A novel protocol for determination of pfhrp2 deletion status in Plasmodium falciparum

23 Jul 2020

Abstract excerpt

Histidine-rich protein 2 (HRP2) detecting rapid diagnostic tests (RDTs) have played an important role in enabling prompt malaria diagnosis in remote locations. However, emergence of pfhrp2 deleted parasites is threatening the efficacy of RDTs, and the World Health Organization (WHO) has highlighted surveillance of these deletions as a priority. Nested PCR is used to confirm pfhrp2 deletion but is costly and...

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PMID: 32702040
DOI: 10.1371/journal.pone.0236369

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