Article
miRNAs-Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study.
Journal of immunology research - 1 Jan 2020
Milanesi Elena, Dobre Maria, Bucuroiu Alina Ioana, Herlea Vlad, Manuc Teodora Ecaterina, Salvi Alessandro, De Petro Giuseppina, Manuc Mircea, Becheanu Gabriel
Abstract excerpt
microRNAs (miRNAs) have been proposed as promising molecular biomarkers for diagnosis, prognosis, and responsive therapeutic targets in different types of cancer, including colorectal cancer (CRC). In this study, we evaluated the expression levels of 84 cancer-associated miRNAs in a cohort of 39 human samples comprising 13 peritumoral and 26 tumoral tissues from surgical specimens of CRC patients. KRAS mutations...
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