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Article

Inherited variant in NFκB-1 promoter is associated with increased risk of IBD in an Algerian population and modulates SOX9 binding.

Cancer reports (Hoboken, N.J.) - 1 Jun 2020

Hamadou Imene, Garritano Sonia, Romanel Alessandro, Naimi Dalila, Hammada Talel, Demichelis Francesca

Abstract excerpt

BACKGROUND: The link between inflammation and cancer development was intensively studied in the last decade. To date, few studies explored the association between inflammatory genes and colorectal cancer (CRC) development. AIM: The present study aimed to evaluate the implication of three single nucleotide polymorphisms (SNPs), rs28362491 ins/del -94 ATTG in NFκB1, rs6920220 (G/A) in TNFAIP3, and rs419598 (C/T) in...

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Share to Algeria
Share to Incidence
Share to Inflammatory Bowel Diseases
Share to NF-kappa B p50 Subunit
Share to Prognosis
Share to Promoter Regions, Genetic
Share to Protein Binding
Share to SOX9 Transcription Factor

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Identifiers

PMID: 32671985
DOI: 10.1002/cnr2.1240
PMCID: PMC7941421

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