Article
Nix alone is sufficient to convert female Aedes aegypti into fertile males and myo-sex is needed for male flight.
Proceedings of the National Academy of Sciences of the United States of America - 28 Jul 2020
Aryan Azadeh, Anderson Michelle A E, Biedler James K, Qi Yumin, Overcash Justin M, Naumenko Anastasia N, Sharakhova Maria V, Mao Chunhong, Adelman Zach N, Tu Zhijian
Abstract excerpt
A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow fever mosquito, Aedes aegyptiNix, a gene in the M-locus, was shown to be a male-determining factor (M factor) as somatic knockout of Nix led to feminized males (M/m) while transient expression of Nix resulted in partially masculinized females (m/m), with male reproductive organs but retained female antennae. It was not clear...
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