Article
Perinatal nicotine exposure‐induced transgenerational asthma: Effects of reexposure in F1 gestation
12 Jul 2020
Abstract excerpt
In a rat model, perinatal nicotine exposure results in an epigenetically driven multi- and trans-generationally transmitted asthmatic phenotype that tends to wane over successive generations. However, the effect of repeat nicotine exposure during the F1 (Filial 1) gestational period on the transmitted phenotype is unknown. Using a well-established rat model, we compared lung function, mesenchymal markers of...
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