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Article

Inter- and transgenerational epigenetic inheritance: evidence in asthma and COPD?

30 Apr 2015

Abstract excerpt

Evidence is now emerging that early life environment can have lifelong effects on metabolic, cardiovascular, and pulmonary function in offspring, a concept also known as fetal or developmental programming. In mammals, developmental programming is thought to occur mainly via epigenetic mechanisms, which include DNA methylation, histone modifications, and expression of non-coding RNAs. The effects of developmental...

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PMID: 26052354
DOI: 10.1186/s13148-015-0085-1

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