Progress in treating chronic granulomatous disease

Abstract excerpt

Summary Chronic granulomatous disease is a primary immunodeficiency due to a defect in one of six subunits that make up the nicotinamide adenine dinucleotide phosphate oxidase complex. The most commonly defective protein, gp91phox, is inherited in an X‐linked fashion; other defects have autosomal recessive inheritance. Bacterial and fungal infections are common presentations, although inflammatory complications...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAR-T cell therapy research
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Share to Virus-based gene therapy research