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Article

Gene therapy for chronic granulomatous disease

22 Nov 2007

Abstract excerpt

Patients with chronic granulomatous disease (CGD) cannot generate reactive oxygen metabolites, and suffer from severe recurrent infections and dysregulated inflammation. Haematopoietic stem cell transplantation is the only established option for definitive cure for patients with a suitable donor and is indicated when conventional prophylaxis and therapy with antimicrobial medication fail. Gene therapy has the...

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PMID: 18034646
DOI: 10.1517/14712598.7.12.1799

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