Article
Clinically significant genomic alterations in the Chinese and Western patients with intrahepatic cholangiocarcinoma.
BMC cancer - 12 Feb 2021
Xu Shifeng, Guo Yuan, Zeng Yanwu, Song Zhijian, Zhu Xiaodan, Fan Ning, Zhang Zhilei, Ren Guibing, Zang Yunjin, Rao Wei
Abstract excerpt
BACKGROUND: The goal of this study is to disclose the clinically significant genomic alterations in the Chinese and Western patients with intrahepatic cholangiocarcinoma. METHODS: A total of 86 Chinese patients were enrolled in this study. A panel of 579 pan-cancer genes was sequenced for the qualified samples from these patients. Driver genes, actionability, and tumor mutational burden were inferred and compared...
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