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Article

Therapeutic targeting of metabolic alterations in acute respiratory distress syndrome.

European respiratory review : an official journal of the European Respiratory Society - 30 Jun 2020

Robinson Matthew John, Krasnodembskaya Anna D

Abstract excerpt

Acute respiratory distress syndrome (ARDS) remains a significant source of mortality in critically ill patients. Characterised by acute, widespread alveolar inflammation and pulmonary oedema, its pathophysiological heterogeneity has meant that targeted treatments have remained elusive. Metabolomic analysis has made initial steps in characterising the underlying metabolic derangements of ARDS as an indicator of...

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Identifiers

PMID: 32620587
DOI: 10.1183/16000617.0114-2020
PMCID: PMC9488567

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