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The Variant rs1784042 of the SIDT2 Gene is Associated with Metabolic Syndrome through Low HDL-c Levels in a Mexican Population.

Genes - 14 Oct 2020

León-Reyes Guadalupe, Rivera-Paredez Berenice, López Juan Carlos Fernandez, Ramírez-Salazar Eric G, Aquino-Gálvez Arnoldo, Gallegos-Carrillo Katia, Denova-Gutiérrez Edgar, Salmerón Jorge, Velázquez-Cruz Rafael

Abstract excerpt

The Mexican population has one of the highest prevalences of metabolic syndrome (MetS) worldwide. The aim of this study was to investigate the association of single-nucleotide polymorphisms (SNPs) with MetS and its components. First, we performed a pilot Genome-wide association study (GWAS) scan on a sub-sample derived from the Health Workers Cohort Study (HWCS) (n = 411). Based on GWAS results, we selected the...

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Identifiers

PMID: 33066450
DOI: 10.3390/genes11101192
PMCID: PMC7602182

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