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Toward a New Molecular Taxonomy of Diffuse Large B-cell Lymphoma.

Cancer discovery - 1 Sept 2020

Ennishi Daisuke, Hsi Eric D, Steidl Christian, Scott David W

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) represents a grouping of clinically and biologically heterogeneous tumors. Application of advanced molecular technology has significantly expanded our knowledge of DLBCL pathobiology, allowing identification of subgroups with common, potentially targetable, biological themes. Here, we review the recent molecular analyses that could provide a paradigm shift to a new taxonomy,...

Topics

Antineoplastic Agents
Biomarkers, Tumor
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Genetic Heterogeneity
Humans
Lymphoma, Large B-Cell, Diffuse
Molecular Targeted Therapy
Mutation
Precision Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

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Identifiers

PMID: 32616477
DOI: 10.1158/2159-8290.CD-20-0174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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