Article
CircFOXO3 rs12196996, a polymorphism at the gene flanking intron, is associated with circFOXO3 levels and the risk of coronary artery disease.
Aging - 2 Jul 2020
Zhou Yu-Lan, Wu Wei-Peng, Cheng Jie, Liang Li-Li, Cen Jin-Ming, Chen Can, Liu Xinguang, Xiong Xing-Dong
Abstract excerpt
CircFOXO3 plays an important role in the pathogenesis of coronary artery disease (CAD). Single nucleotide polymorphisms (SNPs) at circRNA flanking introns may change its back-splicing and influence circRNA formation. Here, we aimed to investigate the influence of the polymorphisms at the circFOXO3 flanking introns on individual susceptibility to CAD. A total of 1185 individuals were included in the case-control...
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