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Article

Neuronal RNA‐binding protein dysfunction in multiple sclerosis cortex

1 Jul 2020

Abstract excerpt

OBJECTIVE: Neurodegeneration is thought to be the primary cause of neurological disability in multiple sclerosis (MS). Dysfunctional RNA-binding proteins (RBPs) including their mislocalization from nucleus to cytoplasm, stress granule formation, and altered RNA metabolism have been found to underlie neurodegeneration in amyotrophic lateral sclerosis and frontotemporal dementia. Yet, little is known about the role...

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PMID: 32608162
DOI: 10.1002/acn3.51103

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