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Article

Counterbalancing the time-dependent effect on the human mitochondrial DNA molecular clock.

BMC evolutionary biology - 29 Jun 2020

Cabrera Vicente M

Abstract excerpt

BACKGROUND: The molecular clock is an important genetic tool for estimating evolutionary timescales. However, the detection of a time-dependent effect on substitution rate estimates complicates its application. It has been suggested that demographic processes could be the main cause of this confounding effect. In the present study, I propose a new algorithm for estimating the coalescent age of phylogenetically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32600249
DOI: 10.1186/s12862-020-01640-5
PMCID: PMC7325269

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