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Article

Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome

26 Jun 2020

Abstract excerpt

OBJECTIVE: Psoriasis is a chronic inflammatory skin disease that is thought to affect ∼2% of the global population. Psoriasis has been associated with ∼30% increased risk of developing type 2 diabetes (T2D), with numerous studies reporting that psoriasis is an independent risk-factor for T2D, separate from underlying obesity. Separately, studies of skin-specific transgenic mice have reported altered whole-body...

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PMID: 32599074
DOI: 10.1016/j.molmet.2020.101047

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