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Article

Sex differences in bicuspid aortic valve disease

27 Jun 2020

Abstract excerpt

Bicuspid aortic valve (BAV), the most frequent congenital heart disease, is characterized by an uneven distribution between sexes. BAV is three to four times more frequent in men than in women which could be associated with a reduced dosage of X chromosome genes. In addition, BAV has a multifactorial inheritance, low penetrance and variable phenotypes that may lead to different form of valve degeneration and...

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PMID: 32599025
DOI: 10.1016/j.pcad.2020.06.004

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