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Article

Genotype of CDC73 germline mutation determines risk of parathyroid cancer.

Endocrine-related cancer - 1 Sept 2020

Li Yulong, Zhang Jianhua, Adikaram Poorni R, Welch James, Guan Bin, Weinstein Lee S, Chen Haobin, Simonds William F

Abstract excerpt

Mutation of the CDC73 gene, which encodes parafibromin, has been linked with parathyroid cancer. However, no correlation between genotypes of germline CDC73 mutations and the risk of parathyroid cancer has been known. In this study, subjects with germline CDC73 mutations were identified from the participants of two clinical protocols at National Institutes of Health (Discovery Cohort) and from the literature...

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Identifiers

PMID: 32590342
DOI: 10.1530/ERC-20-0149
PMCID: PMC8802173

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