Article
Spectrum of α-globin gene mutations in the Kerman Province of Iran.
Hemoglobin - 1 Jan 2010
Saleh-Gohari Nasrollah, Khosravi-Mashizi Arezo
Abstract excerpt
Mutation of the α-globin gene may result in α-thalassemia (α-thal) which is characterized by a reduction or complete absence of the gene expression. In this study, 607 individuals with low levels of blood cell indices and normal Hb A(2) were referred to our laboratory for investigation of any α-thal mutations. We used the gap-polymerase chain reaction (gap-PCR) method and an α-globin strip assay kit to detect the...
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