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Article

Sexual Differentiation Is Coordinately Regulated by Cryptococcus neoformans CRK1 and GAT1.

Genes - 19 Jun 2020

Liu Kuang-Hung, Shen Wei-Chiang

Abstract excerpt

The heterothallic basidiomycetous fungus Cryptococcus neoformans has two mating types, MATa and MATα. Morphological progression of bisexual reproduction in C. neoformans is as follows: yeast to hyphal transition, filament extension, basidium formation, meiosis, and sporulation. C. neoformans Cdk-related kinase 1 (CRK1) is a negative regulator of bisexual mating. In this study, we characterized the morphological...

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Identifiers

PMID: 32575488
DOI: 10.3390/genes11060669
PMCID: PMC7349709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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