The vitamin D receptor Taq I polymorphism is associated with reduced VDR and increased PDIA3 protein levels in human intestinal fibroblasts.

doi:10.1016/j.jsbmb.2020.105720

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Article

The vitamin D receptor Taq I polymorphism is associated with reduced VDR and increased PDIA3 protein levels in human intestinal fibroblasts.

The Journal of steroid biochemistry and molecular biology - 1 Sept 2020

Gisbert-Ferrándiz Laura, Cosin-Roger Jesus, Hernández Carlos, Macias-Ceja Dulce C, Ortiz-Masiá Dolores, Salvador Pedro, Wildenberg M E, Esplugues Juan V, Alós Rafael, Navarro Francisco, Calatayud Sara, Barrachina María D

Abstract excerpt

The synonymous single nucleotide polymorphism (SNP) rs731236, located in the vitamin D receptor (VDR) gene (Taq I) has been associated with both decreased levels of the protein in peripheral blood mononuclear cells and a fibrosis-related complication in Crohn´s disease (CD). Interactions between VDR and a protein-disulfide isomerase-associated 3 (PDIA3) in the regulation of extracellular matrix have been reported...

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PMID: 32565249
DOI: 10.1016/j.jsbmb.2020.105720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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