Article
Gene-environment interaction between APOA5 c.553G>T and pregnancy in hypertriglyceridemia-induced acute pancreatitis.
Journal of clinical lipidology - 1 Jan 2000
Pu Na, Yang Qi, Shi Xiao-Lei, Chen Wei-Wei, Li Xiao-Yao, Zhang Guo-Fu, Li Gang, Li Bai-Qiang, Ke Lu, Tong Zhi-Hui, Cooper David N, Chen Jian-Min, Li Wei-Qin, Li Jie-Shou
Abstract excerpt
BACKGROUND: The etiology of hypertriglyceridemia (HTG) and, consequently, HTG-induced acute pancreatitis (HTG-AP), is complex. OBJECTIVE: Herein, we explore a possible gene-environment interaction between APOA5 c.553G>T (p.185Gly>Cys, rs2075291), a common variant associated with altered triglyceride levels, and pregnancy in HTG-AP. METHODS: We enrolled 318 Chinese HTG-AP patients and divided them into 3 distinct...
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