Article
Dual decline in gait speed and cognition is associated with future dementia: evidence for a phenotype.
Age and ageing - 23 Oct 2020
Montero-Odasso Manuel, Speechley Mark, Muir-Hunter Susan W, Pieruccini-Faria Frederico, Sarquis-Adamson Yanina, Hachinski Vladimir, Bherer Louis, Borrie Michael, Wells Jennie, Garg Amit X, Tian Qu, Ferrucci Luigi, Bray Nick W, Cullen Stephanie, Mahon Joel, Titus Josh, Camicioli Richard
Abstract excerpt
BACKGROUND: concurrent declines in gait speed and cognition have been associated with future dementia. However, the clinical profile of 'dual decliners', those with concomitant decline in both gait speed and cognition, has not been yet described. We aimed to describe the phenotype and the risk for incident dementia of those who present with dual decline in comparison with non-dual decliners. METHODS: prospective...
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