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Article

Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers.

Acta pharmacologica Sinica - 1 Feb 2021

Li Ying, Dong Ya-Ping, Qian You-Wen, Yu Le-Xing, Wen Wen, Cui Xiu-Liang, Wang Hong-Yang

Abstract excerpt

Identification of the functional impact of mutated and altered genes in cancer is critical for implementing precision oncology and drug repurposing. In recent years, the emergence of multiomics data from large, well-characterized patient cohorts has provided us with an unprecedented opportunity to address this problem. In this study, we investigated survival-associated genes across 26 cancer types and found that...

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Identifiers

PMID: 32555508
DOI: 10.1038/s41401-020-0451-1
PMCID: PMC8027787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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