Article
Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.
Gene - 10 Sept 2020
Rao Shitao, Shi Mai, Han Xinyu, Lam Marco Ho Bun, Chien Wai Tong, Zhou Keying, Liu Guangming, Wing Yun Kwok, So Hon-Cheong, Waye Mary Miu Yee
Abstract excerpt
BACKGROUND: The genetic basis of suicide attempts (SA) remains unclear. Especially the role of copy number variations (CNVs) remains to be elucidated. The present study aimed to identify susceptibility variants associated with SA among Chinese with major depressive disorder (MDD), covering both CNVs and single-nucleotide polymorphisms (SNPs). METHODS: We conducted a genome-wide association study (GWAS) on MDD...
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