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[Effect of Signal Transduction Pathway Gene Mutations on the One- course Induced Remission Rate and Analysis of Clinical Characteristics in Patients with CBF-AML].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2020

Fan Li-Fang, Xu Jing, Chen Xiu-Hua, Tian Ting-Ting, Xie Juan, Hu Jin-Jun, Guo Zhi-Ping, Tan Yan-Hong, Xu Zhi-Fang, Ren Fang-Gang, Zhang Yao-Fang, Luo Ming, Ren Wei-Xiao, Wang Hong-Wei

Abstract excerpt

OBJECTIVE: To investigate the effect of other gene mutations outside the fusion gene on the first complete remission (CR1) induced by one course of induction chemotherapy in patients with core binding factor-associated acute myeloid leukemia (CBF-AML). METHODS: DNA was extracted from bone marrow or peripheral blood samples of newly diagnosed CBF-AML patients admitted to the Hematology Department of the Second...

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PMID: 32552936
DOI: 10.19746/j.cnki.issn.1009-2137.2020.03.011

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