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Article

Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein.

Analytical chemistry - 21 Jul 2020

Song Yanling, Song Jia, Wei Xinyu, Huang Mengjiao, Sun Miao, Zhu Lin, Lin Bingqian, Shen Haicong, Zhu Zhi, Yang Chaoyong

Abstract excerpt

The World Health Organization has declared the outbreak of a novel coronavirus (SARS-CoV-2 or 2019-nCoV) as a global pandemic. However, the mechanisms behind the coronavirus infection are not yet fully understood, nor are there any targeted treatments or vaccines. In this study, we identified high-binding-affinity aptamers targeting SARS-CoV-2 RBD, using an ACE2 competition-based aptamer selection strategy and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32551560
DOI: 10.1021/acs.analchem.0c01394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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