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Article

circRNA MYLK Accelerates Cervical Cancer via Up-Regulation of RHEB and Activation of mTOR Signaling

1 May 2020

Abstract excerpt

BACKGROUND: Growing evidence directly suggested that circular RNAs (circRNAs) are crucial contributors in the course of cervical cancer (CC) onset and progression. Nevertheless, a large number of circRNAs have not been fully addressed in their function and underlying mechanisms during CC etiology. PURPOSE: Our study focused on the function of circRNA MYLK (myosin light chain kinase), one novel tumor-related...

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Share to Circular RNAs in diseases
Share to Endometrial and Cervical Cancer Treatments
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PMID: 32547198
DOI: 10.2147/cmar.s238172

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Related research

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Research trail→

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circRNA MYLK Accelerates Cervical Cancer via Up-Regulation of RHEB and Activation of mTOR SignalingPMID 32547198Read ↗

CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signalingSemantic proximity Read ↗

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathwaySemantic proximity Read ↗

Circ_0001247 functions as a miR-1270 sponge to accelerate cervical cancer progression by up-regulating ZEB2 expression levelSemantic proximity Read ↗

circ-MYBL2 Serves As A Sponge For miR-361-3p Promoting Cervical Cancer Cells Proliferation And InvasionSemantic proximity Read ↗

CircAMOTL1 Promotes Tumorigenesis Through miR-526b/SIK2 Axis in Cervical CancerSemantic proximity Read ↗

Circ-MEG3 inhibits the malignant proliferation of human cervical cancer cellsSemantic proximity Read ↗

Circular RNA HIPK3 Promotes EMT of Cervical Cancer Through Sponging miR-338-3p to Up-Regulate HIF-1αSemantic proximity Read ↗

The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complexSemantic proximity Read ↗

Circular RNA circRNA_0000285 promotes cervical cancer development by regulating FUS.Semantic proximity Read ↗

Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer ProgressionSemantic proximity Read ↗

Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axisSemantic proximity Read ↗

ALKBH5-mediated m6A modification of circCCDC134 facilitates cervical cancer metastasis by enhancing HIF1A transcriptionSemantic proximity Read ↗

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