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The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex

30 Jan 2021

Abstract excerpt

BACKGROUND: As a novel type of non-coding RNA, circular RNAs (circRNAs) play a critical role in the initiation and development of various diseases, including cancer. However, the exact function of circRNAs in human cervical cancer remains largely unknown. METHODS: We identified the circRNA signature of upregulated circRNAs between cervical cancer and paired adjacent normal tissues. Using two different cohorts and...

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Circular RNAs in diseases
Endometrial and Cervical Cancer Treatments
MicroRNA in disease regulation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33516252
DOI: 10.1186/s13046-021-01849-2

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