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Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells

15 Jun 2020

Abstract excerpt

Two new lathyrane-type diterpenoids, jatropodagins A and B (1 and 2), and five known analogues (3–7), were isolated from the stems of Jatropha podagrica. Their structures and absolute configurations were elucidated by spectroscopic data and calculated ECD analyses. The cytotoxicities of all the lathyrane-type diterpenoids (1–7) were evaluated against two human osteosarcoma cell lines (Saos-2 and MG-63). Compound...

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PMID: 32538674
DOI: 10.1080/14786419.2020.1779719

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