Article
Novel approach to incorporate information about recessive lethal genes increases the accuracy of genomic prediction for mortality traits.
Heredity - 1 Sept 2020
Gebreyesus Grum, Sahana Goutam, Christian Sørensen A, Lund Mogens S, Su Guosheng
Abstract excerpt
The genetic underpinnings of calf mortality can be partly polygenic and partly due to deleterious effects of recessive lethal alleles. Prediction of the genetic merits of selection candidates should thus take into account both genetic components contributing to calf mortality. However, simultaneously modeling polygenic risk and recessive lethal allele effects in genomic prediction is challenging due to effects...
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