Article
A systematic assessment of mycobacterial F1 -ATPase subunit ε's role in latent ATPase hydrolysis.
The FEBS journal - 1 Feb 2021
Wong Chui-Fann, Lau Aik-Meng, Harikishore Amaravadhi, Saw Wuan-Geok, Shin Joon, Ragunathan Priya, Bhushan Shashi, Ngan So-Fong Cam, Sze Siu Kwan, Bates Roderick W, Dick Thomas, Grüber Gerhard
Abstract excerpt
In contrast to most bacteria, the mycobacterial F1 FO -ATP synthase (α3 :β3 :γ:δ:ε:a:b:b':c9 ) does not perform ATP hydrolysis-driven proton translocation. Although subunits α, γ and ε of the catalytic F1 -ATPase component α3 :β3 :γ:ε have all been implicated in the suppression of the enzyme's ATPase activity, the mechanism remains poorly defined. Here, we brought the central stalk subunit ε into focus by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.