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Article

Mutant p53 as an Antigen in Cancer Immunotherapy.

International journal of molecular sciences - 8 Jun 2020

Sobhani Navid, D'Angelo Alberto, Wang Xu, Young Ken H, Generali Daniele, Li Yong

Abstract excerpt

The p53 tumor suppressor plays a pivotal role in cancer and infectious disease. Many oncology treatments are now calling on immunotherapy approaches, and scores of studies have investigated the role of p53 antibodies in cancer diagnosis and therapy. This review summarizes the current knowledge from the preliminary evidence that suggests a potential role of p53 as an antigen in the adaptive immune response and as...

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Share to Tumor Suppressor Protein p53
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigen Presentation

Share to Antigens, Neoplasm

Share to Biomarkers, Tumor

Share to Gene Expression Regulation, Neoplastic

Share to Immunotherapy

Share to Proteolysis

Source

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Identifiers

PMID: 32521648
DOI: 10.3390/ijms21114087
PMCID: PMC7312027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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