Article
Genome-wide detection of copy number variants in European autochthonous and commercial pig breeds by whole-genome sequencing of DNA pools identified breed-characterising copy number states.
Animal genetics - 1 Aug 2020
Bovo S, Ribani A, Muñoz M, Alves E, Araujo J P, Bozzi R, Charneca R, Di Palma F, Etherington G, Fernandez A I, García F, García-Casco J, Karolyi D, Gallo M, Gvozdanović K, Martins J M, Mercat M J, Núñez Y, Quintanilla R, Radović Č, Razmaite V, Riquet J, Savić R, Schiavo G, Škrlep M, Usai G, Utzeri V J, Zimmer C, Ovilo C, Fontanesi L
Abstract excerpt
In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic resources for this species. The genome of 725 pigs was sequenced using a breed-specific DNA pooling approach (30-35 animals per pool) obtaining an average depth per pool of 42×. This approach maximised CNV discovery...
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