Article
Identification of genome-wide copy number variations among diverse pig breeds by array CGH.
BMC genomics - 24 Dec 2012
Li Yan, Mei Shuqi, Zhang Xuying, Peng Xianwen, Liu Gang, Tao Hu, Wu Huayu, Jiang Siwen, Xiong Yuanzhu, Li Fenge
Abstract excerpt
BACKGROUND: Recent studies have shown that copy number variation (CNV) in mammalian genomes contributes to phenotypic diversity, including health and disease status. In domestic pigs, CNV has been catalogued by several reports, but the extent of CNV and the phenotypic effects are far from clear. The goal of this study was to identify CNV regions (CNVRs) in pigs based on array comparative genome hybridization...
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