Article
Diffuse follicular lymphoma variant with a typical diagnostic pattern and an unusually aggressive clinical presentation.
International journal of hematology - 1 Aug 2020
Martín-Moro Fernando, Marquet-Palomanes Juan, Piris-Villaespesa Miguel, Lopez-Jiménez Javier, García-Cosío Mónica
Abstract excerpt
Diffuse follicular lymphoma (FL) variant is a rare condition that shows distinctive clinical, morphological, immunophenotypic, and molecular features that distinguish it from classical FL. Diffuse FL variant is characterized by a predominantly diffuse growth pattern, absence of the t (14;18) IGH/BCL2 translocation, CD23 expression, and presence of 1p36 deletion. Gene mutations involving STAT6 have been reported,...
Topics
- Aged, 80 and over
- Chromosome Deletion
- Chromosomes, Human, Pair 1
- Female
- Gene Expression
- Humans
- Immunophenotyping
- Lymph Nodes
- Lymphoma, Follicular
- Mutation
- Phosphorylation