Article
A 16-plex Y-SNP typing system based on allele-specific PCR for the genotyping of Chinese Y-chromosomal haplogroups.
Legal medicine (Tokyo, Japan) - 1 Sept 2020
Zhou Zhihan, Zhou Yuxiang, Yao Yining, Qian Jinglei, Liu Baonian, Yang Qinrui, Shao Chengchen, Li Hui, Sun Kuan, Tang Qiqun, Xie Jianhui
Abstract excerpt
Y-chromosomal SNP (Y-SNP), with its stable inheritance and low mutation, can provide Supplementary information in forensic investigation. While commonly used Y-chromosomal STR haplotypes show their limitations, typing of Y-SNP would become a powerful complement. In this study, a 16-plex Y-SNP typing system based on allele-specific PCR (AS-PCR) was developed to discriminate four dominant Y-chromosomal haplogroups...
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