Article
Associations of ATF4 gene polymorphisms with schizophrenia in male patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008
Qu Mei, Tang Fulei, Wang Lifang, Yan Hao, Han Yonghua, Yan Jun, Yue Weihua, Zhang Dai
Abstract excerpt
Activating transcription factor 4 (ATF4) is considered as a positional candidate gene for schizophrenia due to its location at chromosome 22q13, a region linked to schizophrenia. Furthermore, as protein interaction partner of ATF4, disrupted in schizophrenia 1 (DISC1) and its signal pathway implicated in the pathophysiology of schizophrenia have been widely supported by a number of genetic and neurobiological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
