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miR-623 suppresses cell proliferation, migration and invasion through direct inhibition of XRCC5 in breast cancer

5 Jun 2020

Abstract excerpt

BACKGROUND/AIMS: MicroRNAs (miRNAs) are short, non-coding RNA molecules that control gene expression trough negative translational regulation. MiR-623 is a tumor suppressor, and it's function and mechanism in breast cancer has not been reported. RESULTS: Exogenous overexpression of miR-623 suppressed cell proliferation, migration and invasion, meanwhile, but promoted cell apoptosis. MiR-623 knockdown displayed...

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PMID: 32501811
DOI: 10.18632/aging.103182

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