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Article

3'-UTR Polymorphisms of Vitamin B-Related Genes Are Associated with Osteoporosis and Osteoporotic Vertebral Compression Fractures (OVCFs) in Postmenopausal Women.

Genes - 2 Jun 2020

Ahn Tae-Keun, Kim Jung Oh, An Hui Jeong, Park Han Sung, Choi Un Yong, Sohn Seil, Kim Kyoung-Tae, Kim Nam Keun, Han In-Bo

Abstract excerpt

As life expectancy increases, the prevalence of osteoporosis is increasing. In addition to vitamin D which is well established to have an association with osteoporosis, B vitamins, such as thiamine, folate (vitamin B9), and cobalamin (vitamin B12), could affect bone metabolism, bone quality, and fracture risk in humans by influencing homocysteine/folate metabolism. Despite the crucial role of B vitamins in bone...

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Identifiers

PMID: 32498429
DOI: 10.3390/genes11060612
PMCID: PMC7349196

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