In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction

Abstract excerpt

The development of a vaccine able to prevent infection or severe disease course of SARS-CoV-2 is a priority to stem the current COVID-19 pandemic and to be better prepared for future flare-ups.To accelerate T-cell immunogen design, many current approaches are employing epitope prediction strategies.Although such approaches have great merit, it is also important that unbiased approaches to characterizing the...

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