Article
The Impact of Recessive Deleterious Variation on Signals of Adaptive Introgression in Human Populations.
Genetics - 1 Jul 2020
Zhang Xinjun, Kim Bernard, Lohmueller Kirk E, Huerta-Sánchez Emilia
Abstract excerpt
Admixture with archaic hominins has altered the landscape of genomic variation in modern human populations. Several gene regions have been identified previously as candidates of adaptive introgression (AI) that facilitated human adaptation to specific environments. However, simulation-based studies have suggested that population genetic processes other than adaptive mutations, such as heterosis from recessive...
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