Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses

Abstract excerpt

Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden. Since vaccines or specific treatments are not available for most viral infections, the discovery of direct-acting antivirals (DAA) is an urgent...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to interferon and immune responses
• Share to RNA Interference and Gene Delivery
• Share to Viral Infections and Immunology Research