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Article

Unusual mtDNA Control Region Length Heteroplasmy in the COS-7 Cell Line.

Genes - 30 May 2020

Kozhukhar Nataliya, Mitta Sunil, Alexeyev Mikhail F

Abstract excerpt

The COS-7 cell line is a workhorse of virology research. To expand this cell line's utility and to enable studies on mitochondrial DNA (mtDNA) transcription and replication, we determined the complete nucleotide sequence of its mitochondrial genome by Sanger sequencing. In contrast to other available mtDNA sequences from Chlorocebus aethiops, the mtDNA of the COS-7 cell line was found to contain a variable number...

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Identifiers

PMID: 32486194
DOI: 10.3390/genes11060607
PMCID: PMC7348793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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