Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders

1 Jun 2020

Abstract excerpt

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that is associated with repetitive traumatic brain injury (TBI). CTE is known to share similar neuropathological features with Alzheimer's disease (AD), but little is known about the molecular properties in CTE. To better understand the neuropathological mechanism of TBI-related disorders, we conducted transcriptome sequencing analysis of CTE...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to S100 Proteins and Annexins
Share to Traumatic Brain Injury Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32483284
DOI: 10.1038/s41598-020-65916-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of transcriptome signatures in head trauma-related neurodegenerative disordersPMID 32483284Read ↗

A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy.Semantic proximity Read ↗

WGCNA and Machine Learning for Screening Potential Biomarkers in traumatic brain injurySemantic proximity Read ↗

Thyroid hormone T4 mitigates traumatic brain injury in mice by dynamically remodeling cell type specific genes, pathways, and networks in hippocampus and frontal cortexSemantic proximity Read ↗

Spatially resolved transcriptomics reveals a unique disease signature and potential biomarkers for chronic traumatic encephalopathySemantic proximity Read ↗

Exploring the pathogenesis of traumatic brain injury and traumatic epilepsy based on bioinformatics analysisSemantic proximity Read ↗

Proteomic Analysis of Human Chronic Traumatic Encephalopathy Brain Implicates Proteasome and Ribosome Dysfunction in Disease ProgressionSemantic proximity Read ↗

Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathySemantic proximity Read ↗

Mild traumatic brain injury induces memory deficits with alteration of gene expression profileSemantic proximity Read ↗

Single Cell Molecular Alterations Reveal Pathogenesis and Targets of Concussive Brain InjurySemantic proximity Read ↗

Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44 and S100a4 as Treatment TargetsSemantic proximity Read ↗

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injurySemantic proximity Read ↗

Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological DisordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.