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Epigenetic age acceleration in follicular fluid and markers of ovarian response among women undergoing IVF

18 Jun 2024

Abstract excerpt

STUDY QUESTION: Are markers of epigenetic age acceleration in follicular fluid associated with outcomes of ovarian stimulation? SUMMARY ANSWER: Increased epigenetic age acceleration of follicular fluid using the Horvath clock, but not other epigenetic clocks (GrimAge and Granulosa Cell), was associated with lower peak estradiol levels and decreased number of total and mature oocytes. WHAT IS KNOWN ALREADY: In...

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Share to Epigenetics and DNA Methylation
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PMID: 38890131
DOI: 10.1093/humrep/deae136

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