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Restoring aged stem cell functionality: Current progress and future directions.

Stem cells (Dayton, Ohio) - 1 Sept 2020

Spehar Kevin, Pan Andrew, Beerman Isabel

Abstract excerpt

Stem cell dysfunction is a hallmark of aging, associated with the decline of physical and cognitive abilities of humans and other mammals [Cell 2013;153:1194]. Therefore, it has become an active area of research within the aging and stem cell fields, and various techniques have been employed to mitigate the decline of stem cell function both in vitro and in vivo. While some techniques developed in model organisms...

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PMID: 32473067
DOI: 10.1002/stem.3234
PMCID: PMC7483369

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