Article
HLA-B*51 allelic and carrier frequency in Kazakhstan: insights into Behçet's disease prevalence in Central Asia.
Internal and emergency medicine - 1 Mar 2021
Poddighe Dimitri, Turganbekova Aida, Mukusheva Zaure, Abdirakhmanova Altynay, Assylbekova Maikesh, Abdrakhmanova Saniya
Abstract excerpt
Behçet's disease (BD) is a systemic vasculitis whose prevalence varies according to the ethnicity. HLA-B*51 is a well-known genetic factor predisposing to BD: populations with higher HLA-B*51 allelic frequencies are also those with a greater disease prevalence, as occurs in the Silk Road countries. However, the BD prevalence is unknown in many countries, including Kazakhstan and, in general, Central Asia, despite...
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