Article
Computable Phenotype Implementation for a National, Multicenter Pragmatic Clinical Trial: Lessons Learned From ADAPTABLE.
Circulation. Cardiovascular quality and outcomes - 1 Jun 2020
Ahmad Faraz S, Ricket Iben M, Hammill Bradley G, Eskenazi Lisa, Robertson Holly R, Curtis Lesley H, Dobi Cecilia D, Girotra Saket, Haynes Kevin, Kizer Jorge R, Kripalani Sunil, Roe Mathew T, Roumie Christianne L, Waitman Russ, Jones W Schuyler, Weiner Mark G
Abstract excerpt
BACKGROUND: Many large-scale cardiovascular clinical trials are plagued with escalating costs and low enrollment. Implementing a computable phenotype, which is a set of executable algorithms, to identify a group of clinical characteristics derivable from electronic health records or administrative claims records, is essential to successful recruitment in large-scale pragmatic clinical trials. This methods paper...
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