Article
Electronic health records based phenotyping in next-generation clinical trials: a perspective from the NIH Health Care Systems Collaboratory.
Journal of the American Medical Informatics Association : JAMIA - 1 Dec 2013
Richesson Rachel L, Hammond W Ed, Nahm Meredith, Wixted Douglas, Simon Gregory E, Robinson Jennifer G, Bauck Alan E, Cifelli Denise, Smerek Michelle M, Dickerson John, Laws Reesa L, Madigan Rosemary A, Rusincovitch Shelley A, Kluchar Cynthia, Califf Robert M
Abstract excerpt
Widespread sharing of data from electronic health records and patient-reported outcomes can strengthen the national capacity for conducting cost-effective clinical trials and allow research to be embedded within routine care delivery. While pragmatic clinical trials (PCTs) have been performed for decades, they now can draw on rich sources of clinical and operational data that are continuously fed back to inform...
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